PDBsum entry 7vdm

Membrane protein

PDB id: 7vdm

Contents

Protein chains

217 a.a.

339 a.a.

55 a.a.

229 a.a.

253 a.a.

Ligands

ARG-PRO-LYS

CLR

PDB id:

7vdm

Name:

Membrane protein

Title:

Cryo-em structure of pseudoallergen receptor mrgprx2 complex with substance p

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: gng2. Gene: mrgprx2, mrgx2.

Authors:

Y.Li,F.Yang

Key ref:

L.Yu and y.fang Cryo-Em structure of pseudoallergen receptor mrgprx2 with substance p. To be published, . PubMed id: 34789875

Date:

07-Sep-21 Release date: 01-Dec-21

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 217 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 339 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 55 a.a.

Protein chain

No UniProt id for this chain

Struc: 229 a.a.

Protein chain

Q96LB1  (MRGX2_HUMAN) -  Mas-related G-protein coupled receptor member X2 from Homo sapiens

Seq: 330 a.a.

Struc: 253 a.a.

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????