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PDBsum entry 7uik

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protein dna_rna metals Protein-protein interface(s) links
Transcription PDB id
7uik

 

 

 

 

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Contents
Protein chains
89 a.a.
111 a.a.
65 a.a.
110 a.a.
220 a.a.
729 a.a.
895 a.a.
DNA/RNA
Metals
_ZN ×4
PDB id:
7uik
Name: Transcription
Title: Mediator-pic early (tail a + upstream DNA & activator)
Structure: DNA (38-mer). Chain: x. Engineered: yes. DNA (37-mer). Chain: y. Engineered: yes. Regulatory protein gal4. Chain: t, u. Engineered: yes.
Source: Saccharomyces cerevisiae. Organism_taxid: 559292. Expressed in: escherichia coli. Expression_system_taxid: 562. Saccharomyces cerevisiae s288c. Gene: gal4, ypl248c. Strain: atcc 204508 / s288c. Strain: atcc 204508 / s288c
Authors: J.J.Gorbea Colon,S.-F.Chen,K.L.Tsai,K.Murakami
Key ref: J.J.Gorbea colon et al. Structural basis of a transcription pre-Initiation co on a divergent promoter.. Mol cell, . PubMed id: 36731470
Date:
29-Mar-22     Release date:   01-Mar-23    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P04386  (GAL4_YEAST) -  Regulatory protein GAL4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Seq:
Struc:
 
Seq:
Struc:
881 a.a.
89 a.a.
Protein chain
Pfam   ArchSchema ?
P19659  (MED15_YEAST) -  Mediator of RNA polymerase II transcription subunit 15 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1081 a.a.
111 a.a.
Protein chain
Pfam   ArchSchema ?
Q12124  (MED2_YEAST) -  Mediator of RNA polymerase II transcription subunit 2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Seq:
Struc:
431 a.a.
65 a.a.
Protein chain
Pfam   ArchSchema ?
P40356  (MED3_YEAST) -  Mediator of RNA polymerase II transcription subunit 3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Seq:
Struc:
397 a.a.
110 a.a.
Protein chain
Pfam   ArchSchema ?
P19263  (MED14_YEAST) -  Mediator of RNA polymerase II transcription subunit 14 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1082 a.a.
220 a.a.
Protein chain
Pfam   ArchSchema ?
P53114  (MED5_YEAST) -  Mediator of RNA polymerase II transcription subunit 5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1132 a.a.
729 a.a.
Protein chain
Pfam   ArchSchema ?
P32259  (MED16_YEAST) -  Mediator of RNA polymerase II transcription subunit 16 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Seq:
Struc:
 
Seq:
Struc:
974 a.a.
895 a.a.
Key:    PfamA domain  Secondary structure

DNA/RNA chains
  A-C-C-G-G-A-G-G-A-C-A-G-T-C-C-T-C-C-C-G-A-C-T-G-A-C-T-G-A-C-G-T-C-G-T-A-C-G 38 bases
  C-G-T-A-C-G-A-C-G-T-C-A-G-T-C-A-G-T-C-G-G-G-A-G-G-A-C-T-G-T-C-C-T-C-C-G-G 37 bases

 

 

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