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UniProt functional annotation for O60895 | ||
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| UniProt code: O60895. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL. {ECO:0000269|PubMed:22102369, ECO:0000269|PubMed:9620797}. |
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| Subunit: | |
Heterodimer of CALCRL and RAMP2. {ECO:0000269|PubMed:30115739}. |
| Subcellular location: | |
Membrane; Single-pass type I membrane protein. |
| Tissue specificity: | |
Strongly expressed in lung, breast, immune system and fetal tissues. {ECO:0000269|PubMed:9620797}. |
| Similarity: | |
Belongs to the RAMP family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.