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PDBsum entry 7rxp

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protein Protein-protein interface(s) links
Immune system PDB id
7rxp

 

 

 

 

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Contents
Protein chains
219 a.a.
235 a.a.
65 a.a.
Waters ×528
PDB id:
7rxp
Name: Immune system
Title: Fab1512 in complex with thE C-terminal alpha-tsr domain of p. Falciparum
Structure: Fab1512 light chain. Chain: l. Engineered: yes. Fab1512 heavy chain. Chain: h. Engineered: yes. Circumsporozoite protein. Chain: a. Fragment: c-terminal alpha-tsr domain (unp residues 309-375).
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Plasmodium falciparum (isolate 3d7). Organism_taxid: 36329. Strain: isolate 3d7. Gene: pf3d7_0304600.
Resolution:
1.76Å     R-factor:   0.178     R-free:   0.205
Authors: T.Pholcharee,D.Oyen,I.A.Wilson
Key ref: n.beutler et al. (2022). A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum. Plos Pathog., 18, e1010409. PubMed id: 35344575
Date:
23-Aug-21     Release date:   16-Mar-22    
PROCHECK
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 Headers
 References

Protein chain
No UniProt id for this chain
Struc: 219 a.a.
Protein chain
No UniProt id for this chain
Struc: 235 a.a.
Protein chain
Pfam   ArchSchema ?
Q7K740  (Q7K740_PLAF7) -  Circumsporozoite protein from Plasmodium falciparum (isolate 3D7)
Seq:
Struc:
397 a.a.
65 a.a.
Key:    PfamA domain  Secondary structure

 

 
Plos Pathog. 18:e1010409 (2022)
PubMed id: 35344575  
 
 
A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
n.beutler, t.pholcharee, d.oyen, y.flores-garcia, r.s.mace.garcia, j.calla, m.parren, l.yang, w.volkmuth, e.locke, d.emerling, a.early, d.neafsey, e.winzeler, c.r.king, f.zad.r.burton, i.a.wilson, t.f.rogers.
 
  ABSTRACT  
 
No abstract given.

 

 

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