| UniProt functional annotation for Q8U093 | |||
| UniProt code: Q8U093. |
| Organism: | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1). | |
| Taxonomy: | Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus. | |
| Function: | The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. {ECO:0000250}. | |
| Catalytic activity: | Reaction=(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D- glyceraldehyde 3-phosphate + H2O + L-tryptophan; Xref=Rhea:RHEA:10532, ChEBI:CHEBI:15377, ChEBI:CHEBI:33384, ChEBI:CHEBI:57912, ChEBI:CHEBI:58866, ChEBI:CHEBI:59776; EC=4.2.1.20; | |
| Cofactor: | Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; Evidence={ECO:0000250}; | |
| Pathway: | Amino-acid biosynthesis; L-tryptophan biosynthesis; L- tryptophan from chorismate: step 5/5. | |
| Subunit: | Tetramer of two alpha and two beta chains. {ECO:0000250}. | |
| Similarity: | Belongs to the TrpB family. {ECO:0000305}. | |
Annotations taken from UniProtKB at the EBI.