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PDBsum entry 7r5r
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protein dna_rna Protein-protein interface(s) links
Cell cycle PDB id
7r5r

 

 

 

 

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Contents
Protein chains
99 a.a.
78 a.a.
98 a.a.
92 a.a.
94 a.a.
103 a.a.
21 a.a.
22 a.a.
DNA/RNA
PDB id:
7r5r
Name: Cell cycle
Title: Structure of the human ccan cenp-a alpha-satellite complex
Structure: Histone h3-like centromeric protein a. Chain: a, e. Synonym: centromere autoantigen a,centromere protein a,cenp-a. Engineered: yes. Histone h4. Chain: b, f. Engineered: yes. Histone h2a type 1-c. Chain: c, g.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cenpa. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hist1h4a, h4/a, h4fa, hist1h4b, h4/i, h4fi, hist1h4c, h4/g, h4fg, hist1h4d, h4/b, h4fb, hist1h4e, h4/j, h4fj, hist1h4f, h4/c, h4fc, hist1h4h, h4/h, h4fh, hist1h4i, h4/m, h4fm, hist1h4j, h4/e,
Authors: S.Yatskevich,K.W.Muir,D.Bellini,Z.Zhang,J.Yang,T.Tischer,M.Predin, T.Dendooven,S.H.Mclaughlin,D.Barford
Key ref: S.Yatskevich et al. Structure of the human inner kinetochore bound to a centromeric cenp-A nucleosome.. Science, . PubMed id: 35420891
Date:
11-Feb-22     Release date:   27-Apr-22    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P49450  (CENPA_HUMAN) -  Histone H3-like centromeric protein A from Homo sapiens
Seq:
Struc: 		140 a.a.
99 a.a.
Protein chains
Pfam   ArchSchema ?
P62805  (H4_HUMAN) -  Histone H4 from Homo sapiens
Seq:
Struc: 		103 a.a.
78 a.a.
Protein chain
Pfam   ArchSchema ?
Q93077  (H2A1C_HUMAN) -  Histone H2A type 1-C from Homo sapiens
Seq:
Struc: 		130 a.a.
98 a.a.
Protein chains
Pfam   ArchSchema ?
P62807  (H2B1C_HUMAN) -  Histone H2B type 1-C/E/F/G/I from Homo sapiens
Seq:
Struc: 		126 a.a.
92 a.a.
Protein chain
Pfam   ArchSchema ?
P49450  (CENPA_HUMAN) -  Histone H3-like centromeric protein A from Homo sapiens
Seq:
Struc: 		140 a.a.
94 a.a.
Protein chain
Pfam   ArchSchema ?
Q93077  (H2A1C_HUMAN) -  Histone H2A type 1-C from Homo sapiens
Seq:
Struc: 		130 a.a.
103 a.a.
Protein chain
Pfam   ArchSchema ?
Q03188  (CENPC_HUMAN) -  Centromere protein C from Homo sapiens
Seq:
Struc: 		 
Seq:
Struc: 		943 a.a.
21 a.a.
Protein chain
Pfam   ArchSchema ?
Q03188  (CENPC_HUMAN) -  Centromere protein C from Homo sapiens
Seq:
Struc: 		 
Seq:
Struc: 		943 a.a.
22 a.a.
Key:    PfamA domain  Secondary structure

DNA/RNA chains
  C-C-A-A-T-T-C-C-A-G-A-T-A-C-T-A-C-A-A-A-A-A-G-A-G-T-G-T-T-T-C-A-A-A-A-C-T-G-C- 133 bases
  A-T-A-T-G-T-T-C-A-C-A-T-A-A-A-A-A-C-T-A-G-A-C-A-G-A-A-G-C-A-T-T-C-T-C-A-G-A-A- 133 bases

 Enzyme reactions 
   Enzyme class: Chains A, B, C, D, E, F, G, H, K, L: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 

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