PDBsum entry 7ouk

Transport protein

PDB id: 7ouk

Contents

Protein chains

1033 a.a.

156 a.a.

Ligands

LMT ×8

1K8 ×2

EDO ×14

OCT ×3

C14 ×3

GOL ×6

D10

DDR

DDQ

SO4 ×3

LPX ×2

Waters ×365

PDB id:

7ouk

Name:

Transport protein

Title:

Bdm88855 inhibitor bound to the transmembrane domain of acrb

Structure:

Multidrug efflux pump subunit acrb. Chain: a, b, c. Synonym: acrab-tolc multidrug efflux pump subunit acrb,acridine resistance protein b. Engineered: yes. Darpin. Chain: d, e. Engineered: yes

Source:

Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: acrb, acre, b0462, jw0451. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c43. Synthetic construct. Organism_taxid: 32630.

Resolution:

2.60Å R-factor: 0.238 R-free: 0.263

Authors:

H.K.Tam,W.E.Foong,K.M.Pos

Key ref:

H.K.Tam et al. Bdm88855 inhibitor bound to the transmembrane domain. To be published, . PubMed id: 35013254

Date:

12-Jun-21 Release date: 29-Dec-21

Protein chains

P31224  (ACRB_ECOLI) -  Multidrug efflux pump subunit AcrB from Escherichia coli (strain K12)

Seq: 1049 a.a.

Struc: 1033 a.a.

Protein chains

No UniProt id for this chain

Struc: 156 a.a.

Enzyme reactions

• Enzyme class: Chains A, B, C: E.C.?