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UniProt functional annotation for A0A059VAZ3 | ||
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| UniProt code: A0A059VAZ3. |
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| Organism: | |
Meiothermus taiwanensis. |
| Taxonomy: | |
Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Meiothermus. |
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| Function: | |
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. {ECO:0000256|HAMAP-Rule:MF_01973}. |
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| Catalytic activity: | |
Reaction=Hydrolysis of proteins in presence of ATP.; EC=3.4.21.53; Evidence={ECO:0000256|HAMAP-Rule:MF_01973, ECO:0000256|PIRNR:PIRNR001174, ECO:0000256|PROSITE-ProRule:PRU01122}; |
| Subunit: | |
Homohexamer. Organized in a ring with a central cavity. {ECO:0000256|HAMAP-Rule:MF_01973, ECO:0000256|PIRNR:PIRNR001174}. |
| Subcellular location: | |
Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|HAMAP-Rule:MF_01973, ECO:0000256|PIRNR:PIRNR001174}. |
| Induction: | |
By heat shock. {ECO:0000256|HAMAP-Rule:MF_01973}. |
| Similarity: | |
Belongs to the peptidase S16 family. {ECO:0000256|HAMAP- Rule:MF_01973, ECO:0000256|PIRNR:PIRNR001174, ECO:0000256|PROSITE- ProRule:PRU01122, ECO:0000256|RuleBase:RU000591}. |
Annotations taken from UniProtKB at the EBI.