PDBsum entry 7c8r

Viral protein

PDB id: 7c8r

Contents

Protein chain

301 a.a.

Ligands

TG3

Waters ×84

PDB id:

7c8r

Name:

Viral protein

Title:

Complex structure of sars-cov-2 3cl protease with tg-0203770

Structure:

3c-like proteinase. Chain: a. Synonym: 3cl-pro,3clp,main protease,mpro,non-structural protein 5, nsp5,sars coronavirus main proteinase. Engineered: yes

Source:

Severe acute respiratory syndrome coronavirus 2. 2019-ncov. Organism_taxid: 2697049. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.30Å R-factor: 0.200 R-free: 0.248

Authors:

C.C.Lee,A.H.J.Wang,C.J.Kuo,P.H.Liang

Key ref:

C.J.Kuo et al. Complex structures and cellular activities of the pot sars-Cov-2 3clpro inhibitors guiding drug discovery a covid-19. To be published, .

Date:

03-Jun-20 Release date: 17-Jun-20

Protein chain

P0DTD1  (R1AB_SARS2) -

Enzyme reactions

• Enzyme class: E.C.3.4.22.69 - Sars coronavirus main proteinase.