UniProt functional annotation for P75811

UniProt code: P75811.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: Regulates the expression of a number of genes involved in biofilm formation and stress response. Target genes include six stress- response transcriptional regulators: csgD, which is a master regulator of biofilm formation, appY, sxy, ycgF, fimB and rcdA itself. This indicates that a large number of genes must be regulated indirectly via these transcriptional regulators. Acts by binding to the upstream region of its target genes. {ECO:0000269|PubMed:23233451}.
 
Induction: Autoregulated. {ECO:0000269|PubMed:23233451}.
Miscellaneous: Has a strong cooperative DNA-binding mode, leading to aggregation of RcdA-DNA complexes. {ECO:0000305|PubMed:23233451}.

Annotations taken from UniProtKB at the EBI.