PDBsum entry 7wui

Membrane protein

PDB id: 7wui

Contents

Protein chains

230 a.a.

338 a.a.

55 a.a.

126 a.a.

245 a.a.

220 a.a.

11 a.a.

PDB id:

7wui

Name:

Membrane protein

Title:

Tethered peptide activation mechanism of adhesion gpcrs adgrg2 and adgrg4

Structure:

Mini-gs. Chain: a. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: baculovirus expression vector pfastbac1-hm. Expression_system_taxid: 274590. Gene: gnb1. Gene: gng2. Lama glama. Organism_taxid: 9844.

Authors:

S.C.Guo,Q.T.He,P.Xiao,J.P.Sun,X.Yu

Key ref:

P.Xiao et al. Tethered peptide activation mechanism of the adhesion adgrg2 and adgrg4.. Nature, . PubMed id: 35418677

Date:

08-Feb-22 Release date: 27-Apr-22

Protein chain

P63092  (GNAS2_HUMAN) -  Guanine nucleotide-binding protein G(s) subunit alpha isoforms short from Homo sapiens

Seq: 394 a.a.

Struc: 230 a.a.*

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 230 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 338 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 55 a.a.

Protein chain

No UniProt id for this chain

Struc: 126 a.a.

Protein chain

Q8CJ12  (AGRG2_MOUSE) -  Adhesion G-protein coupled receptor G2 from Mus musculus

Seq: 1009 a.a.

Struc: 245 a.a.

Protein chain

No UniProt id for this chain

Struc: 220 a.a.

Protein chain

Q8CJ12  (AGRG2_MOUSE) -  Adhesion G-protein coupled receptor G2 from Mus musculus

Seq: 1009 a.a.

Struc: 11 a.a.*

* PDB and UniProt seqs differ at 200 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????