PDBsum entry 7vh0

Membrane protein

PDB id: 7vh0

Contents

Protein chains

273 a.a.

215 a.a.

336 a.a.

54 a.a.

231 a.a.

Ligands

JEV

PDB id:

7vh0

Name:

Membrane protein

Title:

Mt2-remalteon-gi complex

Structure:

Melatonin receptor type 1b. Chain: a. Synonym: mel-1b-r,mel1b receptor. Engineered: yes. Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: b. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: mtnr1b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnai1. Rattus norvegicus. Norway rat.

Authors:

Q.G.Wang,Q.Y.Lu

Key ref:

Q.G.Wang and q.y.lu Structure of mt2-Gi complex at 3.5 angstroms. To be published, . PubMed id: 35075127

Date:

20-Sep-21 Release date: 02-Mar-22

Protein chain

P49286  (MTR1B_HUMAN) -  Melatonin receptor type 1B from Homo sapiens

Seq: 362 a.a.

Struc: 273 a.a.*

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 215 a.a.

Protein chain

P54311  (GBB1_RAT) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Rattus norvegicus

Seq: 340 a.a.

Struc: 336 a.a.*

Protein chain

No UniProt id for this chain

Struc: 54 a.a.

Protein chain

No UniProt id for this chain

Struc: 231 a.a.

* PDB and UniProt seqs differ at 6 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain B: E.C.3.6.5.- - ?????