PDBsum entry 7t6u

Signaling protein

PDB id: 7t6u

Contents

Protein chains

219 a.a.

337 a.a.

57 a.a.

232 a.a.

299 a.a.

Ligands

GLN-LYS-PHE-THR-SER-TRP-PHE-QXV

PLM ×2

PDB id:

7t6u

Name:

Signaling protein

Title:

Structure of the human fpr2-gi complex with cgen-855a

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: spodoptera. Expression_system_taxid: 7106. Rattus. Organism_taxid: 10114. Gene: gnb1.

Authors:

Y.W.Zhuang

Key ref:

Y.W.Zhuang Molecular recognition of formylpeptides and diverse a by the formylpeptide receptors fpr1 and fpr2. To be published, . PubMed id: 35217703

Date:

14-Dec-21 Release date: 30-Mar-22

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 219 a.a.*

Protein chain

P54311  (GBB1_RAT) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Rattus norvegicus

Seq: 340 a.a.

Struc: 337 a.a.*

Protein chain

P63212  (GBG2_BOVIN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Bos taurus

Seq: 71 a.a.

Struc: 57 a.a.

Protein chain

No UniProt id for this chain

Struc: 232 a.a.

Protein chain

P25090  (FPR2_HUMAN) -  N-formyl peptide receptor 2 from Homo sapiens

Seq: 351 a.a.

Struc: 299 a.a.

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????