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PDBsum entry 7sk6
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Signaling protein
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PDB id
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7sk6
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Contents |
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300 a.a.
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59 a.a.
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101 a.a.
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125 a.a.
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PDB id:
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| Name: |
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Signaling protein
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Title:
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Cryo-em structure of human ackr3 in complex with chemokine n-terminal mutant cxcl12_lrhq and an intracellular fab
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Structure:
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Atypical chemokine receptor 3. Chain: a. Synonym: c-x-c chemokine receptor type 7,cxc-r7,cxcr-7,chemokine orphan receptor 1,g-protein coupled receptor 159,g-protein coupled receptor rdc1 homolog,rdc-1. Engineered: yes. Stromal cell-derived factor 1. Chain: b. Synonym: sdf-1,hsdf-1,c-x-c motif chemokine 12,intercrine reduced in
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: ackr3, cmkor1, cxcr7, gpr159, rdc1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: cxcl12, sdf1, sdf1a, sdf1b. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768.
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Authors:
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Y.C.Yen,C.T.Schafer,M.Gustavsson,T.M.Handel,J.J.G.Tesmer
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Key ref:
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Y.C.Yen
et al.
(2022).
Structures of atypical chemokine receptor 3 reveal th for its promiscuity and signaling bias..
Sci adv,
8,
n8063.
PubMed id:
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Date:
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19-Oct-21
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Release date:
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27-Jul-22
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PROCHECK
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Headers
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References
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Links
