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PDBsum entry 7sk3
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Signaling protein/immune system
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PDB id
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7sk3
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Contents |
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304 a.a.
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68 a.a.
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105 a.a.
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123 a.a.
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106 a.a.
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125 a.a.
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PDB id:
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| Name: |
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Signaling protein/immune system
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Title:
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Cryo-em structure of ackr3 in complex with cxcl12, an intracellular fab, and an extracellular fab
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Structure:
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Atypical chemokine receptor 3. Chain: a. Synonym: c-x-c chemokine receptor type 7,cxc-r7,cxcr-7,chemokine orphan receptor 1,g-protein coupled receptor 159,g-protein coupled receptor rdc1 homolog,rdc-1. Engineered: yes. Stromal cell-derived factor 1. Chain: b. Fragment: unp residues 22-89.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: ackr3, cmkor1, cxcr7, gpr159, rdc1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: cxcl12, sdf1, sdf1a, sdf1b. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768.
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Authors:
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Y.C.Yen,C.T.Schafer,M.Gustavsson,T.M.Handel,J.J.G.Tesmer
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Key ref:
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Y.C.Yen
et al.
(2022).
Structures of atypical chemokine receptor 3 reveal th for its promiscuity and signaling bias..
Sci adv,
8,
n8063.
PubMed id:
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Date:
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19-Oct-21
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Release date:
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27-Jul-22
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PROCHECK
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Headers
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References
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P25106
(ACKR3_HUMAN) -
Atypical chemokine receptor 3 from Homo sapiens
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Seq:
Struc:
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362 a.a.
304 a.a.
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P48061
(SDF1_HUMAN) -
Stromal cell-derived factor 1 from Homo sapiens
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Seq:
Struc:
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93 a.a.
68 a.a.
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Links
