PDBsum entry 7rg9

Membrane protein

PDB id: 7rg9

Contents

Protein chains

220 a.a.

339 a.a.

232 a.a.

59 a.a.

128 a.a.

268 a.a.

PDB id:

7rg9

Name:

Membrane protein

Title:

Cryo-em of human glucagon-like peptide 1 receptor glp-1r in apo form

Structure:

Isoform gnas-2 of guanine nucleotide-binding protein g(s) subunit alpha isoforms short. Chain: a. Synonym: adenylate cyclase-stimulating g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnas, gnas1, gsp. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: gnb1. Mus musculus. Organism_taxid: 10090.

Authors:

B.Sun,B.K.Kobilka,K.W.Sloop,D.Feng,T.S.Kobilka

Key ref:

B.Sun et al. (2022). Structural determinants of dual incretin receptor ago tirzepatide.. Proc natl acad sci usa, 119, 06119. PubMed id: 35333651

Date:

14-Jul-21 Release date: 13-Apr-22

Protein chain

P26831  (NAGH_CLOPE) -  Hyaluronoglucosaminidase from Clostridium perfringens (strain 13 / Type A)

Seq: 1628 a.a.

Struc: 220 a.a.*

Protein chain

No UniProt id for this chain

Struc: 339 a.a.

Protein chain

No UniProt id for this chain

Struc: 232 a.a.

Protein chain

No UniProt id for this chain

Struc: 59 a.a.

Protein chain

No UniProt id for this chain

Struc: 128 a.a.

Protein chain

No UniProt id for this chain

Struc: 268 a.a.

* PDB and UniProt seqs differ at 196 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????