PDBsum entry 7o7f

Signaling protein

PDB id: 7o7f

Contents

Protein chains

219 a.a.

338 a.a.

300 a.a.

58 a.a.

67 a.a.

221 a.a.

217 a.a.

PDB id:

7o7f

Name:

Signaling protein

Title:

Structural basis of the activation of the cc chemokine receptor 5 by a chemokine agonist

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. C-c chemokine receptor type 5.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Bos taurus. Bovine. Organism_taxid: 9913.

Authors:

P.Isaikina,C.-J.Tsai,N.B.Dietz,F.Pamula,K.N.Goldie,G.F.X.Schertler, T.Maier,H.Stahlberg,X.Deupi,S.Grzesiek

Key ref:

P.Isaikina et al. (2021). Structural basis of the activation of the cc chemokin receptor 5 by a chemokine agonist.. Sci adv, 7, . PubMed id: 34134983

Date:

13-Apr-21 Release date: 30-Jun-21

Protein chain

Q8EG34  (Q8EG34_SHEON) -  Extracellular iron oxide respiratory system surface decaheme cytochrome c component MtrC from Shewanella oneidensis (strain ATCC 700550 / JCM 31522 / CIP 106686 / LMG 19005 / NCIMB 14063 / MR-1)

Seq: 671 a.a.

Struc: 219 a.a.*

Protein chain

No UniProt id for this chain

Struc: 338 a.a.

Protein chain

No UniProt id for this chain

Struc: 300 a.a.

Protein chain

No UniProt id for this chain

Struc: 58 a.a.

Protein chain

No UniProt id for this chain

Struc: 67 a.a.

Protein chain

No UniProt id for this chain

Struc: 221 a.a.

Protein chain

No UniProt id for this chain

Struc: 217 a.a.

* PDB and UniProt seqs differ at 184 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????