PDBsum entry 7f2o

Membrane protein

PDB id: 7f2o

Contents

Protein chains

230 a.a.

341 a.a.

287 a.a.

232 a.a.

51 a.a.

Ligands

ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG

PDB id:

7f2o

Name:

Membrane protein

Title:

Cryo-em structure of the type 2 bradykinin receptor in complex with the bradykinin and an gq protein

Structure:

G subunit q (gi1-gq chimeric). Chain: a. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes. Arg-pro-pro-gly-phe-ser-pro-phe-arg.

Source:

Homo sapiens. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: gnb1. Synthetic: yes.

Authors:

Y.Yin,Y.Jiang

Key ref:

Y.L.Yin et al. (2021). Molecular basis for kinin selectivity and activation human bradykinin receptors.. Nat struct mol biol, 28, 755. PubMed id: 34518695

Date:

11-Jun-21 Release date: 13-Oct-21

Protein chain

No UniProt id for this chain

Struc: 230 a.a.

Protein chain

P54311  (GBB1_RAT) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Rattus norvegicus

Seq: 340 a.a.

Struc: 341 a.a.

Protein chain

P30411  (BKRB2_HUMAN) -  B2 bradykinin receptor from Homo sapiens

Seq: 391 a.a.

Struc: 287 a.a.*

Protein chain

No UniProt id for this chain

Struc: 232 a.a.

Protein chain

P63212  (GBG2_BOVIN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Bos taurus

Seq: 71 a.a.

Struc: 51 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)