PDBsum entry 7ejx

Membrane protein

PDB id: 7ejx

Contents

Protein chains

229 a.a.

216 a.a.

337 a.a.

56 a.a.

233 a.a.

Ligands

J5F

CLR ×3

Waters ×2

PDB id:

7ejx

Name:

Membrane protein

Title:

Structure of the gpr88-gi1 signaling complex bound to a synthetic ligand

Structure:

Probable g-protein coupled receptor 88. Chain: r. Synonym: striatum-specific g-protein coupled receptor. Engineered: yes. Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gpr88, strg. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnai1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.

Authors:

J.Xu,G.Chen,Z.Liu,Y.Du

Key ref:

J.Xu et al. Structure of the gpr88-Gi1 signaling complex. To be published, . PubMed id: 35501348

Date:

02-Apr-21 Release date: 13-Apr-22

Protein chain

Q9GZN0  (GPR88_HUMAN) -  G protein-coupled receptor 88 from Homo sapiens

Seq: 384 a.a.

Struc: 229 a.a.

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 216 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 337 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 56 a.a.

Protein chain

No UniProt id for this chain

Struc: 233 a.a.

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????