PDBsum entry 7eib

Membrane protein

PDB id: 7eib

Contents

Protein chains

295 a.a.

235 a.a.

338 a.a.

51 a.a.

Ligands

LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE

PDB id:

7eib

Name:

Membrane protein

Title:

Cryo-em structure of the type 1 bradykinin receptor in complex with the des-arg10-kallidin and an gq protein

Structure:

B1 bradykinin receptor. Chain: a. Synonym: b1r,bk-1 receptor. Engineered: yes. Mutation: yes. Lys-arg-pro-pro-gly-phe-ser-pro-phe. Chain: d. Engineered: yes. G subunit q (gi1-gq chimeric).

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: bdkrb1, bradyb1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Rattus norvegicus. Rat.

Authors:

Y.Yin,Y.Jiang

Key ref:

Y.L.Yin et al. (2021). Molecular basis for kinin selectivity and activation human bradykinin receptors.. Nat struct mol biol, 28, 755. PubMed id: 34518695

Date:

30-Mar-21 Release date: 13-Oct-21

Protein chain

P46663  (BKRB1_HUMAN) -  B1 bradykinin receptor from Homo sapiens

Seq: 353 a.a.

Struc: 295 a.a.*

Protein chain

No UniProt id for this chain

Struc: 235 a.a.

Protein chain

P54311  (GBB1_RAT) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Rattus norvegicus

Seq: 340 a.a.

Struc: 338 a.a.

Protein chain

P63212  (GBG2_BOVIN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Bos taurus

Seq: 71 a.a.

Struc: 51 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)