PDBsum entry 7eb2

Membrane protein

PDB id: 7eb2

Contents

Protein chains

352 a.a.

339 a.a.

57 a.a.

231 a.a.

678 a.a.

680 a.a.

Ligands

2C0

FN0

PDB id:

7eb2

Name:

Membrane protein

Title:

Cryo-em structure of human gaba(b) receptor-gi protein complex

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Mutation: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell: hi5. Gene: gnb1. Gene: gng2.

Authors:

C.Shen,C.Mao,C.Xu,N.Jin,H.Zhang,D.Shen,Q.Shen,X.Wang,T.Hou,P.Rondard, Z.Chen,J.Pin,Y.Zhang,J.Liu

Date:

08-Mar-21 Release date: 05-May-21

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 352 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 339 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 57 a.a.

Protein chain

No UniProt id for this chain

Struc: 231 a.a.

Protein chain

Q9UBS5  (GABR1_HUMAN) -  Gamma-aminobutyric acid type B receptor subunit 1 from Homo sapiens

Seq: 961 a.a.

Struc: 678 a.a.

Protein chain

O75899  (GABR2_HUMAN) -  Gamma-aminobutyric acid type B receptor subunit 2 from Homo sapiens

Seq: 941 a.a.

Struc: 680 a.a.

* PDB and UniProt seqs differ at 4 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????