PDBsum entry 6yl2

DNA binding protein

PDB id: 6yl2

Contents

Protein chains

192 a.a.

DNA/RNA

PDB id:

6yl2

Name:

DNA binding protein

Title:

Structural and DNA binding studies of the transcriptional repressor rv2506 (bkar) from mycobacterium tuberculosis supports a role in l- leucine catabolism

Structure:

Probable transcriptional regulatory protein (probably tetr- family). Chain: b, a. Engineered: yes. DNA (5'- d( Ap Cp Gp Tp Tp Ap Ap Tp Gp Ap Cp Gp Ap Tp Tp Ap Ap Cp Cp G)-3'). Chain: g. Engineered: yes. DNA (5'-

Source:

Mycobacterium tuberculosis (strain atcc 25618 / h37rv). Organism_taxid: 83332. Gene: rv2506. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Mycobacterium tuberculosis h37rv. Organism_taxid: 83332

Resolution:

3.15Å R-factor: 0.268 R-free: 0.284

Authors:

N.H.Keep,J.E.Pritchard,A.Sula,A.R.Cole,S.L.Kendall

Key ref:

J.E.Pritchard et al. Structural and DNA binding studies of the transcripti repressor rv2506 (bkar) from mycobacterium tuberculos supports a role in l-Leucine catabolism. To be published, .

Date:

06-Apr-20 Release date: 14-Apr-21

Protein chains

O06169  (O06169_MYCTU) -  Probable transcriptional regulatory protein (Probably TetR-family) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Seq: 215 a.a.

Struc: 192 a.a.

DNA/RNA chains

A-C-G-T-T-A-A-T-G-A-C-G-A-T-T-A-A-C-C-G 20 bases

C-G-G-T-T-A-A-T-C-G-T-C-A-T-T-A-A-C-G-T 20 bases

Enzyme reactions

• Enzyme class: E.C.?