UniProt functional annotation for Q02080

UniProt code: Q02080.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
 
Function: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.
 
Subunit: Interacts with HDAC7 (By similarity). Heterodimer. Interacts with HDAC9. {ECO:0000250, ECO:0000269|PubMed:15567413}.
Subcellular location: Nucleus.
Tissue specificity: Expressed in skeletal and cardiac muscle and brain.
Similarity: Belongs to the MEF2 family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.