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UniProt functional annotation for P42485 | ||
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| UniProt code: P42485. |
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| Organism: | |
African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV). |
| Taxonomy: | |
Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes; Asfuvirales; Asfarviridae; Asfivirus. |
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| Function: | |
Suppresses apoptosis in host cell and thus facilitates production of progeny virions (PubMed:9123849, PubMed:18329683). Has the ability to potentially bind to all the members of the proapoptotic Bcl-2 family (PubMed:28053104, PubMed:18329683). {ECO:0000269|PubMed:18329683, ECO:0000269|PubMed:28053104, ECO:0000269|PubMed:9123849}. |
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| Subunit: | |
Interacts with host BECN1 (PubMed:23228131). Interacts with host BID (PubMed:28053104). dInteracts with host BAX (PubMed:28053104). {ECO:0000269|PubMed:23228131, ECO:0000269|PubMed:28053104}. |
| Induction: | |
Expressed early and late in the infection cycle. |
| Similarity: | |
Belongs to the Bcl-2 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.