PDBsum entry 6tzc

Structural protein/apoptosis

PDB id: 6tzc

Contents

Protein chains

367 a.a.

144 a.a.

20 a.a.

Ligands

GLC-GLC

Waters ×126

PDB id:

6tzc

Name:

Structural protein/apoptosis

Title:

Crystal structure of african swine fever virus a179l with the autophagy regulator beclin

Structure:

Maltose/maltodextrin-binding periplasmic protein. Chain: a. Synonym: mmbp,maltodextrin-binding protein,maltose-binding protein, mbp. Engineered: yes. Apoptosis regulator bcl-2 homolog. Chain: b. Engineered: yes. Beclin-1.

Source:

Escherichia coli (strain k12). Organism_taxid: 83333. Strain: k12. Gene: male, b4034, jw3994. Expressed in: escherichia coli. Expression_system_taxid: 562. African swine fever virus (strain badajoz 1971 vero-adapted). Ba71v.

Resolution:

2.41Å R-factor: 0.216 R-free: 0.253

Authors:

S.Banjara,M.Kvansakul,M.G.Hinds

Key ref:

S.Banjara et al. (2019). Crystal structure of african swine fever virus a179l the autophagy regulator beclin.. Viruses, 11, . PubMed id: 31461953

Date:

12-Aug-19 Release date: 20-Nov-19

Protein chain

P0AEX9  (MALE_ECOLI) -  Maltose/maltodextrin-binding periplasmic protein from Escherichia coli (strain K12)

Seq: 396 a.a.

Struc: 367 a.a.*

Protein chain

P42485  (ARBH_ASFB7) -  Apoptosis regulator Bcl-2 homolog from African swine fever virus (strain Badajoz 1971 Vero-adapted)

Seq: 179 a.a.

Struc: 144 a.a.

Protein chain

Q4A1L5  (BECN1_PIG) -  Beclin-1 from Sus scrofa

Seq: 448 a.a.

Struc: 20 a.a.

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chains A, B, C: E.C.?