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UniProt functional annotation for A2QHE5 | ||
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| UniProt code: A2QHE5. |
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| Organism: | |
Aspergillus niger (strain CBS 513.88 / FGSC A1513). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus subgen. Circumdati. |
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| Function: | |
Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4- vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites. {ECO:0000255|HAMAP-Rule:MF_03196, ECO:0000269|PubMed:26083754}. |
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| Catalytic activity: | |
Reaction=(E)-4-coumarate + H(+) = 4-hydroxystyrene + CO2; Xref=Rhea:RHEA:33227, ChEBI:CHEBI:1883, ChEBI:CHEBI:12876, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526; EC=4.1.1.102; Evidence={ECO:0000255|HAMAP-Rule:MF_03196}; |
| Catalytic activity: | |
Reaction=(E)-cinnamate + H(+) = CO2 + styrene; Xref=Rhea:RHEA:46920, ChEBI:CHEBI:15378, ChEBI:CHEBI:15669, ChEBI:CHEBI:16526, ChEBI:CHEBI:27452; EC=4.1.1.102; Evidence={ECO:0000255|HAMAP- Rule:MF_03196, ECO:0000269|PubMed:26083743}; |
| Catalytic activity: | |
Reaction=(E)-ferulate + H(+) = 2-methoxy-4-vinylphenol + CO2; Xref=Rhea:RHEA:33807, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:29749, ChEBI:CHEBI:42438; EC=4.1.1.102; Evidence={ECO:0000255|HAMAP-Rule:MF_03196}; |
| Cofactor: | |
Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000255|HAMAP-Rule:MF_03196, ECO:0000269|PubMed:26083754}; |
| Cofactor: | |
Name=prenyl-FMN; Xref=ChEBI:CHEBI:87746; Evidence={ECO:0000255|HAMAP-Rule:MF_03196, ECO:0000269|PubMed:26083743, ECO:0000269|PubMed:26083754}; Note=Binds 1 prenylated FMN (prenyl-FMN) per subunit. {ECO:0000255|HAMAP-Rule:MF_03196, ECO:0000269|PubMed:26083754}; |
| Subunit: | |
Homodimer. May form higher order oligomers. {ECO:0000255|HAMAP-Rule:MF_03196}. |
| Subcellular location: | |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03196}. |
| Similarity: | |
Belongs to the UbiD family. UbiD-like/FDC subfamily. {ECO:0000255|HAMAP-Rule:MF_03196}. |
Annotations taken from UniProtKB at the EBI.