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UniProt functional annotation for Q2FXJ2 | ||
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| UniProt code: Q2FXJ2. |
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| Organism: | |
Staphylococcus aureus (strain NCTC 8325 / PS 47). |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus. |
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| Function: | |
Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone. {ECO:0000269|PubMed:12823809}. |
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| Subcellular location: | |
Secreted, cell wall {ECO:0000305}; Peptidoglycan- anchor {ECO:0000305}. |
| Induction: | |
Expression was observed only in the late logarithmic and stationary phase. Repressed by the ferric uptake repressor (fur) protein in the presence of iron. |
| Domain: | |
The NEAT 1 domain binds with higher affinity than the NEAT 2 domain haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. {ECO:0000250}. |
| Similarity: | |
Belongs to the IsdH family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.