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UniProt functional annotation for Q9UYX8 | ||
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| UniProt code: Q9UYX8. |
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| Organism: | |
Pyrococcus abyssi (strain GE5 / Orsay). |
| Taxonomy: | |
Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus. |
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| Function: | |
Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity). Regulates activity of NucS endonuclease and prevents non- specific cleavage. {ECO:0000255|HAMAP-Rule:MF_00317, ECO:0000269|PubMed:22431731}. |
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| Subunit: | |
The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA (By similarity). Homotrimer. Interacts with NucS. {ECO:0000250, ECO:0000269|PubMed:19609302, ECO:0000269|PubMed:22431731}. |
| Similarity: | |
Belongs to the PCNA family. {ECO:0000255|HAMAP- Rule:MF_00317}. |
Annotations taken from UniProtKB at the EBI.