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UniProt functional annotation for B1MDI3 | ||
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| UniProt code: B1MDI3. |
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| Organism: | |
Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543) (Mycobacterium abscessus). |
| Taxonomy: | |
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacteroides; Mycobacteroides abscessus. |
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| Function: | |
Specifically methylates guanosine-37 in various tRNAs. {ECO:0000256|ARBA:ARBA00002634, ECO:0000256|HAMAP-Rule:MF_00605, ECO:0000256|RuleBase:RU003464}. |
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| Catalytic activity: | |
Reaction=guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)- methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:36899, Rhea:RHEA-COMP:10145, Rhea:RHEA-COMP:10147, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:73542, ChEBI:CHEBI:74269; EC=2.1.1.228; Evidence={ECO:0000256|ARBA:ARBA00001189, ECO:0000256|HAMAP- Rule:MF_00605, ECO:0000256|RuleBase:RU003464}; |
| Subunit: | |
Homodimer. {ECO:0000256|ARBA:ARBA00011738, ECO:0000256|HAMAP- Rule:MF_00605, ECO:0000256|RuleBase:RU003464}. |
| Subcellular location: | |
Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|HAMAP-Rule:MF_00605, ECO:0000256|RuleBase:RU003464}. |
| Similarity: | |
Belongs to the RNA methyltransferase TrmD family. {ECO:0000256|ARBA:ARBA00007630, ECO:0000256|HAMAP-Rule:MF_00605, ECO:0000256|RuleBase:RU003464}. |
Annotations taken from UniProtKB at the EBI.