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UniProt functional annotation for P0AEX9 | ||
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| UniProt code: P0AEX9. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins such as maltotriose. {ECO:0000269|PubMed:2026607, ECO:0000269|PubMed:2155217, ECO:0000269|PubMed:4215651, ECO:0000269|PubMed:776623}. |
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| Biophysicochemical properties: | |
Kinetic parameters: KM=0.9 uM for maltose {ECO:0000269|PubMed:776623}; KM=2 uM for maltotriose {ECO:0000269|PubMed:776623}; |
| Subunit: | |
The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE). {ECO:0000269|PubMed:2026607, ECO:0000269|PubMed:2155217}. |
| Subcellular location: | |
Periplasm {ECO:0000269|PubMed:4215651}. |
| Induction: | |
Induced by maltose and the transcriptional regulator MalT (PubMed:4215651). Permanently repressed by cold shock in a PNPase- dependent fashion (PubMed:14527658). {ECO:0000269|PubMed:14527658, ECO:0000269|PubMed:4215651}. |
| Similarity: | |
Belongs to the bacterial solute-binding protein 1 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.