PDBsum entry 6kp6

Membrane protein

PDB id: 6kp6

Contents

Protein chain

477 a.a.

PDB id:

6kp6

Name:

Membrane protein

Title:

The structural study of mutation induced inactivation of human muscarinic receptor m4

Structure:

Muscarinic acetylcholine receptor m4,glga glycogen synthase,muscarinic acetylcholine receptor m4. Chain: a. Synonym: glycogen synthase. Engineered: yes. Mutation: yes. Other_details: fusion protein of muscarinic acetylcholine receptor m4 and glga glycogen synthase

Source:

Homo sapiens, pyrococcus abyssi ge5. Human. Organism_taxid: 9606, 272844. Strain: ge5 / orsay. Gene: chrm4, pab2292. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: insect cell.

Resolution:

3.00Å R-factor: 0.233 R-free: 0.264

Authors:

J.J.Wang,M.Wu,L.J.Wu,Z.J.Liu,T.Hua

Date:

14-Aug-19 Release date: 11-Mar-20

Protein chain

P08173  (ACM4_HUMAN) -  Muscarinic acetylcholine receptor M4 from Homo sapiens

Seq: 479 a.a.

Struc: 477 a.a.*

Protein chain

Q9V2J8  (Q9V2J8_PYRAB) -  Glycogen synthase from Pyrococcus abyssi (strain GE5 / Orsay)

Seq: 437 a.a.

Struc: 477 a.a.*

* PDB and UniProt seqs differ at 371 residue positions (black crosses)