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UniProt functional annotation for Q12417 | ||
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| UniProt code: Q12417. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
Involved in pre-mRNA splicing. May also be required for cell cycle progression at G2/M (By similarity). {ECO:0000250, ECO:0000269|PubMed:12554883}. |
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| Subunit: | |
Belongs to the CWC complex (or CEF1-associated complex), a spliceosome subcomplex composed of the U2, U5 and U6 snRNAs and at least BUD13, BUD31, BRR2, CDC40, CEF1, CLF1, CUS1, CWC2, CWC15, CWC21, CWC22, CWC23, CWC24, CWC25, CWC27, ECM2, HSH155, IST3, ISY1, LEA1, MSL1, NTC20, PRP8, PRP9, PRP11, PRP19, PRP21, PRP22, PRP45, PRP46, SLU7, SMB1, SMD1, SMD2, SMD3, SMX2, SMX3, SNT309, SNU114, SPP2, SYF1, SYF2, RSE1 and YJU2. Interacts with CEF1, CLF1, NTC20, PRP45 and SYF1. {ECO:0000269|PubMed:11884590, ECO:0000269|PubMed:12088152, ECO:0000269|PubMed:12554883}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}. |
| Miscellaneous: | |
Present with 1770 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the WD repeat PRL1/PRL2 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.