| UniProt functional annotation for C4R0E6 | |||
| UniProt code: C4R0E6. |
| Organism: | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris). | |
| Taxonomy: | Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Phaffomycetaceae; Komagataella. | |
| Function: | The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. {ECO:0000256|PIRNR:PIRNR025023}. | |
| Subcellular location: | Chromosome, centromere {ECO:0000256|ARBA:ARBA00004584}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR025023}. | |
| Similarity: | Belongs to the SPT4 family. {ECO:0000256|ARBA:ARBA00010464, ECO:0000256|PIRNR:PIRNR025023}. | |
Annotations taken from UniProtKB at the EBI.