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UniProt functional annotation for P07584 | ||
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| UniProt code: P07584. |
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| Organism: | |
Astacus astacus (Noble crayfish) (Astacus fluviatilis). |
| Taxonomy: | |
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea; Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea; Astacoidea; Astacidae; Astacus. |
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| Function: | |
Metalloprotease. This protease prefers to cleave in front of small aliphatic residues (P1'). The presence of Lys or Arg in the P1 and P2 position yields high-turnover substrates. In the P3 position the enzyme prefers Pro > Val > Leu > Ala > Gly. {ECO:0000269|PubMed:2261483}. |
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| Catalytic activity: | |
Reaction=Hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'.; EC=3.4.24.21; Evidence={ECO:0000269|PubMed:2261483, ECO:0000269|Ref.3}; |
| Cofactor: | |
Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000255|PROSITE-ProRule:PRU01211, ECO:0000269|PubMed:1319561, ECO:0000269|PubMed:8756323, ECO:0000269|Ref.3}; Note=Binds 1 zinc ion per subunit. {ECO:0000255|PROSITE- ProRule:PRU01211, ECO:0000269|PubMed:1319561, ECO:0000269|PubMed:8756323, ECO:0000269|Ref.3}; |
| Subunit: | |
Monomer. |
Annotations taken from UniProtKB at the EBI.