PDBsum entry 6eah

Viral protein

PDB id: 6eah

Contents

Protein chains

446 a.a.

Ligands

NAG-NAG-FUC

SO4 ×20

NHE

PDB id:

6eah

Name:

Viral protein

Title:

Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant k394r-s398l stabilized in the prefusion state

Structure:

Fusion glycoprotein f0. Chain: a, b, c. Fragment: rsv f ectodomain. Engineered: yes. Mutation: yes

Source:

Human respiratory syncytial virus. Organism_taxid: 11250. Expressed in: homo sapiens. Expression_system_taxid: 9606.

Resolution:

3.00Å R-factor: 0.194 R-free: 0.219

Authors:

M.B.Battles,J.S.Mclellan

Key ref:

M.B.Battles and j.s.mclellan Structural basis for respiratory syncytial virus fusi inhibitor resistance. To be published, .

Date:

03-Aug-18 Release date: 07-Aug-19

Protein chains

P03420  (FUS_HRSVA) -  Fusion glycoprotein F0 from Human respiratory syncytial virus A (strain A2)

Seq: 574 a.a.

Struc: 446 a.a.*

* PDB and UniProt seqs differ at 9 residue positions (black crosses)