UniProt functional annotation for Q66104

UniProt code: Q66104.

Organism: Carnation Italian ringspot virus (CIRV).
Taxonomy: Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Tolucaviricetes; Tolivirales; Tombusviridae; Procedovirinae; Tombusvirus.
 
Function: Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Binds to short interfering RNAs (siRNAs) with high affinity. Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA. {ECO:0000269|PubMed:14697199, ECO:0000269|PubMed:19254536}.
 
Subunit: Homodimer.
Similarity: Belongs to the tombusvirus protein p19 family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.