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UniProt functional annotation for P0A9V1 | ||
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| UniProt code: P0A9V1. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. {ECO:0000269|PubMed:16765569, ECO:0000269|PubMed:17056748, ECO:0000269|PubMed:18424520}. |
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| Subunit: | |
Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG). {ECO:0000269|PubMed:19500581}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:16079137}. Cell inner membrane {ECO:0000269|PubMed:16079137}; Peripheral membrane protein {ECO:0000269|PubMed:16079137}; Cytoplasmic side {ECO:0000269|PubMed:16079137}. |
| Induction: | |
Transcriptionally regulated by sigma-E factor. {ECO:0000269|PubMed:17056748}. |
| Disruption phenotype: | |
Results in an earlier growth arrest and onset of cell lethality. {ECO:0000269|PubMed:16765569}. |
| Similarity: | |
Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.