PDBsum entry 6wqa

Membrane protein

PDB id: 6wqa

Contents

Protein chain

391 a.a.

Ligands

ZMA

CLR ×3

OLA ×15

OLC ×5

GOL

OLB

Metals

_NA

Waters ×84

PDB id:

6wqa

Name:

Membrane protein

Title:

2.0a angstrom a2a adenosine receptor structure using xfel data collected in helium atmosphere.

Structure:

Adenosine receptor a2a/soluble cytochrome b562 chimera. Chain: a. Synonym: cytochrome b-562. Engineered: yes

Source:

Homo sapiens, escherichia coli. Human. Organism_taxid: 9606, 562. Gene: adora2a, adora2, cybc. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.

Resolution:

2.00Å R-factor: 0.194 R-free: 0.216

Authors:

M.-Y.Lee,J.Geiger,A.Ishchenko,G.W.Han,A.Barty,T.A.White,C.Gati, A.Batyuk,M.S.Hunter,A.Aquila,S.Boutet,U.Weierstall,V.Cherezov,W.Liu

Key ref:

M.-Y.Lee et al. (2020). Harnessing the power of an X-Ray laser for serial crystallography of membrane proteins crystallized in cubic phase. Iucrj, 7, 976.

Date:

28-Apr-20 Release date: 18-Nov-20

Protein chain

P0ABE7  (C562_ECOLX) -  Soluble cytochrome b562 from Escherichia coli

Seq: 128 a.a.

Struc: 391 a.a.*

Protein chain

P29274  (AA2AR_HUMAN) -  Adenosine receptor A2a from Homo sapiens

Seq: 412 a.a.

Struc: 391 a.a.*

* PDB and UniProt seqs differ at 108 residue positions (black crosses)