UniProt functional annotation for P25491

UniProt code: P25491.

Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
 
Function: Probably involved in mitochondrial protein import. Is also required for efficient translocation of pre-pro-alpha-factor. Involved in heme regulation of HAP1, as a component of the high-molecular-weight (HMC) complex. {ECO:0000269|PubMed:11689685}.
 
Subunit: Homodimer. Interacts with HAP1. Component of the HMC including HAP1, SRO9 and YDJ1. {ECO:0000269|PubMed:11689685, ECO:0000269|PubMed:14656432}.
Subcellular location: Cytoplasm. Cytoplasm, perinuclear region. Note=Concentrated in a perinuclear ring as well as in the cytoplasm.
Induction: YDJ1 is a heat shock gene whose expression increases moderately at elevated temperatures.
Miscellaneous: Present with 119000 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.

Annotations taken from UniProtKB at the EBI.