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UniProt functional annotation for Q97VT7 | ||
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| UniProt code: Q97VT7. |
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| Organism: | |
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus). |
| Taxonomy: | |
Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus. |
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| Function: | |
Has a low paraoxonase activity. Also active, but with a lower activity, against other organo-phosphorus insecticides such as Dursban, Coumaphos, pNP-butanoate or parathion. {ECO:0000269|PubMed:15909078}. |
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| Catalytic activity: | |
Reaction=An aryl dialkyl phosphate + H(2)O = dialkyl phosphate + an aryl alcohol.; EC=3.1.8.1; Evidence={ECO:0000269|PubMed:15909078}; |
| Cofactor: | |
Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000269|PubMed:18486146}; Note=Binds 1 Co(2+) ion per subunit. {ECO:0000269|PubMed:18486146}; |
| Cofactor: | |
Name=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000269|PubMed:18486146}; Note=Binds 1 Fe cation per subunit. {ECO:0000269|PubMed:18486146}; |
| Activity regulation: | |
Inactivated by EDTA and o-phenanthroline. {ECO:0000269|PubMed:15909078}. |
| Biophysicochemical properties: | |
Kinetic parameters: KM=0.06 mM for paraoxon (at pH 8.0) {ECO:0000269|PubMed:15909078}; KM=0.205 mM for methyl-paraoxon (at pH 8.0) {ECO:0000269|PubMed:15909078}; pH dependence: Optimum pH is 7.0-9.0. {ECO:0000269|PubMed:15909078}; Temperature dependence: Thermostable. {ECO:0000269|PubMed:15909078}; |
| Subunit: | |
Homodimer. {ECO:0000269|PubMed:18486146}. |
| Similarity: | |
Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family. {ECO:0000255|PROSITE-ProRule:PRU00679}. |
Annotations taken from UniProtKB at the EBI.