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UniProt functional annotation for P56373 | ||
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| UniProt code: P56373. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Receptor for ATP that acts as a ligand-gated cation channel (PubMed:27626375). Plays a role in sensory perception. Required for normal perception of pain. Required for normal taste perception (By similarity). {ECO:0000250|UniProtKB:Q3UR32, ECO:0000269|PubMed:27626375}. |
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| Subunit: | |
Homotrimer (PubMed:27626375). Functional P2XRs are organized as homomeric and heteromeric trimers (By similarity). {ECO:0000250|UniProtKB:P49654, ECO:0000269|PubMed:27626375}. |
| Subcellular location: | |
Cell membrane {ECO:0000269|PubMed:27626375}; Multi-pass membrane protein {ECO:0000269|PubMed:27626375}. |
| Similarity: | |
Belongs to the P2X receptor family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.