PDBsum entry 5ruc

Viral protein, hydrolase

PDB id: 5ruc

Contents

Protein chains

167 a.a.

Ligands

NCA

Waters ×508

PDB id:

5ruc

Name:

Viral protein, hydrolase

Title:

Pandda analysis group deposition -- crystal structure of sars-cov-2 nsp3 macrodomain in complex with zinc000000005878

Structure:

Non-structural protein 3. Chain: a, b. Synonym: nsp3,pl2-pro,papain-like protease,papain-like proteinase,pl- pro. Engineered: yes. Other_details: his6 purification tag and linker (mhhhhhhssgvdlgtenlyfq) cleaved with tev protease

Source:

Severe acute respiratory syndrome coronavirus 2. 2019-ncov. Organism_taxid: 2697049. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.00Å R-factor: 0.157 R-free: 0.170

Authors:

G.J.Correy,I.D.Young,M.C.Thompson,J.S.Fraser

Key ref:

G.J.Correy and j.s.fraser Fragment screen against sars-Cov-2 nsp macrodomain. To be published, . PubMed id: 33853786

Date:

28-Sep-20 Release date: 16-Dec-20

Protein chains

P0DTD1  (R1AB_SARS2) -