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UniProt functional annotation for Q4FTX3 | ||
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| UniProt code: Q4FTX3. |
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| Organism: | |
Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Moraxellaceae; Psychrobacter. |
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| Function: | |
Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. {ECO:0000255|HAMAP-Rule:MF_00125}. |
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| Pathway: | |
Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9. {ECO:0000255|HAMAP-Rule:MF_00125}. |
| Subunit: | |
Heteromultimer composed of HisG and HisZ subunits. {ECO:0000255|HAMAP-Rule:MF_00125}. |
| Subcellular location: | |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00125}. |
| Miscellaneous: | |
This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. |
| Similarity: | |
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily. {ECO:0000255|HAMAP-Rule:MF_00125}. |
| Sequence caution: | |
Sequence=AAZ18535.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.