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PDBsum entry 5j4l
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PDB id:
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Hydrolase
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Title:
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Apo-structure of humanised rada-mutant humrada22f
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Structure:
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DNA repair and recombination protein rada. Chain: a. Engineered: yes. Mutation: yes
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Source:
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Pyrococcus furiosus (strain atcc 43587 / dsm 3638 / jcm 8422 / vc1). Organism_taxid: 186497. Gene: rada, pf1926. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Resolution:
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1.13Å
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R-factor:
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0.125
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R-free:
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0.145
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Authors:
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G.Fischer,M.Marsh,T.Moschetti,T.Sharpe,D.Scott,M.Morgan,H.Ng, J.Skidmore,A.Venkitaraman,C.Abell,T.L.Blundell,M.Hyvonen
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Key ref:
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T.Moschetti
et al.
(2016).
Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J Mol Biol,
428,
4589-4607.
PubMed id:
DOI:
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Date:
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01-Apr-16
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Release date:
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19-Oct-16
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PROCHECK
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Headers
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References
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O74036
(RADA_PYRFU) -
DNA repair and recombination protein RadA from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
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Seq:
Struc:
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349 a.a.
226 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 10 residue positions (black
crosses)
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DOI no:
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J Mol Biol
428:4589-4607
(2016)
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PubMed id:
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Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
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T.Moschetti,
T.Sharpe,
G.Fischer,
M.E.Marsh,
H.K.Ng,
M.Morgan,
D.E.Scott,
T.L.Blundell,
A.R Venkitaraman,
J.Skidmore,
C.Abell,
M.Hyvönen.
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ABSTRACT
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Links
