UniProt functional annotation for Q18DH8

UniProt code: Q18DH8.

Organism: Haloquadratum walsbyi (strain DSM 16790 / HBSQ001).
Taxonomy: Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales; Haloferacaceae; Haloquadratum.
 
Function: Light-driven proton pump. The chromophore contains 78% all- trans- and 22% 13-cis-retinal in the dark and 90% all-trans- and 10% 13-cis-retinal upon illumination with >500 nm light. {ECO:0000269|PubMed:21135094, ECO:0000269|PubMed:22248212, ECO:0000269|PubMed:23720753}.
 
Biophysicochemical properties: Absorption: Abs(max)=552 nm {ECO:0000269|PubMed:21135094, ECO:0000269|PubMed:22248212}; Note=In light-adapted form, max=555 nm. In the mutated form, max=498 nm.;
Subcellular location: Cell membrane {ECO:0000269|PubMed:22248212}; Multi-pass membrane protein {ECO:0000269|PubMed:22248212}.
Ptm: The covalent binding of retinal to the apoprotein, bacterioopsin, generates bacteriorhodopsin. {ECO:0000250}.
Miscellaneous: Different protein aggregation states can be observed, leading to variations in the absorbance maxima. {ECO:0000305|PubMed:22248212}.
Similarity: Belongs to the archaeal/bacterial/fungal opsin family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.