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UniProt functional annotation for P00772 | ||
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| UniProt code: P00772. |
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| Organism: | |
Sus scrofa (Pig). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus. |
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| Function: | |
Acts upon elastin. |
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| Catalytic activity: | |
Reaction=Hydrolysis of proteins, including elastin. Preferential cleavage: Ala-|-Xaa.; EC=3.4.21.36; |
| Cofactor: | |
Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Note=Binds 1 Ca(2+) ion per subunit.; |
| Subcellular location: | |
Secreted. |
| Tissue specificity: | |
Pancreas. Basal layers of the epidermis, hair follicle and sebaceous gland epithelia (at protein level). {ECO:0000269|PubMed:10620133}. |
| Similarity: | |
Belongs to the peptidase S1 family. Elastase subfamily. {ECO:0000255|PROSITE-ProRule:PRU00274}. |
Annotations taken from UniProtKB at the EBI.