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UniProt functional annotation for A8ISN6 | ||
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| UniProt code: A8ISN6. |
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| Organism: | |
Chlamydomonas reinhardtii (Chlamydomonas smithii). |
| Taxonomy: | |
Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae; CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas. |
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| Function: | |
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase- activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Required for targeting proteins to the ciliary membrane by releasing myristoylated protein from unc119 cargo adapters into the cilium. {ECO:0000250|UniProtKB:P36405}. |
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| Subcellular location: | |
Golgi apparatus membrane {ECO:0000250|UniProtKB:P36405}; Peripheral membrane protein {ECO:0000250|UniProtKB:P36405}; Cytoplasmic side {ECO:0000250|UniProtKB:P36405}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:P36405}. Nucleus {ECO:0000250|UniProtKB:P36405}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:P36405}. Cytoplasm {ECO:0000250|UniProtKB:P36405}. Note=Not detected to interphase microtubules. Present on the mitotic spindle. {ECO:0000250|UniProtKB:P36405}. |
| Similarity: | |
Belongs to the small GTPase superfamily. Arf family. {ECO:0000305}. |
| Sequence caution: | |
Sequence=EDP04202.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.