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PDBsum entry 5dcc
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PDB id:
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Transferase
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Title:
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X-ray crystal structure of a tebipenem adduct of l,d transpeptidase 2 from mycobacterium tuberculosis
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Structure:
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L,d-transpeptidase 2. Chain: a, b. Fragment: unp residues 56-408. Synonym: ldt 2,ldt(mt2). Engineered: yes
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Source:
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Mycobacterium tuberculosis. Organism_taxid: 83331. Strain: cdc 1551 / oshkosh. Gene: ldtb, mt2594, v735_02606. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.45Å
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R-factor:
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0.173
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R-free:
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0.214
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Authors:
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Y.Pan,L.Basta,G.Lamichhane,M.A.Bianchet
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Key ref:
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M.A.Bianchet
et al.
(2017).
Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2by biapenem and tebipenem.
BMC Biochem,
18,
8.
PubMed id:
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Date:
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23-Aug-15
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Release date:
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28-Sep-16
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PROCHECK
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Headers
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References
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I6Y9J2
(LDT2_MYCTU) -
L,D-transpeptidase 2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
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Seq:
Struc:
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408 a.a.
352 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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BMC Biochem
18:8
(2017)
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PubMed id:
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Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2by biapenem and tebipenem.
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M.A.Bianchet,
Y.H.Pan,
L.A.B.Basta,
H.Saavedra,
E.P.Lloyd,
P.Kumar,
R.Mattoo,
C.A.Townsend,
G.Lamichhane.
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ABSTRACT
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