PDBsum entry 5bpm

Hydrolase

PDB id: 5bpm

Contents

Protein chain

378 a.a.

Ligands

ATP

Metals

_CL ×2

_MG

_NA

Waters ×418

PDB id:

5bpm

Name:

Hydrolase

Title:

Crystal structure of unhydrolyzed atp bound human hsp70 nbd double mutant e268q+r272k.

Structure:

Heat shock 70 kda protein 1a. Chain: a. Synonym: heat shock 70 kda protein 1,hsp70.1. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hspa1a, hspa1, hsx70. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: ril.

Resolution:

1.83Å R-factor: 0.174 R-free: 0.228

Authors:

D.Narayanan,R.A.Engh

Key ref:

D.Narayanan et al. Nucleotide binding to variants of the hsp70-Nbd.. To be published, .

Date:

28-May-15 Release date: 14-Sep-16

Protein chain

P0DMV8  (HS71A_HUMAN) -  Heat shock 70 kDa protein 1A from Homo sapiens

Seq: 641 a.a.

Struc: 378 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)