PDBsum entry 5ind

Immune system

PDB id: 5ind

Contents

Protein chains

277 a.a.

99 a.a.

Ligands

GLN-ALA-SER-GLN-ASP-VAL-LYS-ASN-TRP ×2

Waters ×415

PDB id:

5ind

Name:

Immune system

Title:

Crystal structure of hla-b5801, a protective hla allele for HIV-1 infection

Structure:

Hla class i histocompatibility antigen, b-58 alpha chain. Chain: a, c. Synonym: bw-58,mhc class i antigen b 58. Engineered: yes. Beta-2-microglobulin. Chain: b, d. Engineered: yes. Gln-ala-ser-gln-asp-val-lys-asn-trp. Chain: e, f.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-b, hlab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: b2m, cdabp0092, hdcma22p. Synthetic: yes. Unidentified.

Resolution:

2.13Å R-factor: 0.189 R-free: 0.229

Authors:

X.Li,J.-H.Wang

Key ref:

X.Li et al. (2016). Crystal structure of HLA-B*5801, a protective HLA allele for HIV-1 infection. Protein Cell, 7, 761-765. PubMed id: 27638468 DOI: 10.1007/s13238-016-0309-y

Date:

07-Mar-16 Release date: 05-Oct-16

Protein chains

P01889  (1B07_HUMAN) -  HLA class I histocompatibility antigen, B alpha chain from Homo sapiens

Seq: 362 a.a.

Struc: 277 a.a.*

Protein chains

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 99 a.a.

* PDB and UniProt seqs differ at 29 residue positions (black crosses)

DOI no: 10.1007/s13238-016-0309-y

Protein Cell 7:761-765 (2016)

PubMed id: 27638468

Crystal structure of HLA-B*5801, a protective HLA allele for HIV-1 infection.

X.Li, P.A.Lamothe, R.Ng, S.Xu, M.Teng, B.D.Walker, J.H.Wang.

ABSTRACT

No abstract given.